Analysis of ligand binding to recombinant human carbonic anhydrases I, II, VII, IX and XIII
Carbonic anhydrases (CAs) are metalloenzymes that catalyze the conversion between carbon dioxide and bicarbonate. Their inhibition can be applied for treatment of different diseases, such as glaucoma, cancer, obesity, epilepsy, osteoporosis, etc. There are nearly 30 small molecule ligands that are u...
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| Format: | Doctoral Thesis |
| Language: | English |
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Lithuanian Academic Libraries Network (LABT)
2013
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| Online Access: | http://vddb.laba.lt/fedora/get/LT-eLABa-0001:E.02~2013~D_20130327_100539-96804/DS.005.1.01.ETD |