Testing the reliability and selectivity of different bone-cell-specific Cre- expressing mouse models for studying bone cell metabolism

Testing the reliability and selectivity of different bone-cell-specific Cre- expressing mouse models for studying bone cell metabolism

Indiana University-Purdue University Indianapolis (IUPUI) === The Cre/loxP system is a tool for targeted recombination of DNA. For applying Cre recombinase-mediated genome modifications, there is a requirement for reliable, high-fidelity, and specific transgenic expression of the Cre recombinase. Th...

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Bibliographic Details
Main Author: Kambrath, Anuradha Valiya
Other Authors: Robling, Alexander G.
Language:en_US
Published: 2016
Subjects:
DMP1-Cre
Ctsk-Cre
Bones > Growth
Bones > Growth > Molecular aspects
Genetic recombination > Research
Recombinant DNA
Gene targeting
Osteocytes
Bone cells
Osteoblasts
Online Access:https://hdl.handle.net/1805/7942

Internet

https://hdl.handle.net/1805/7942

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