Interplay between collapsin response mediator protein 2 (CRMP2) phosphorylation and sumoylation modulates NaV1.7 trafficking

Interplay between collapsin response mediator protein 2 (CRMP2) phosphorylation and sumoylation modulates NaV1.7 trafficking

Indiana University-Purdue University Indianapolis (IUPUI) === The voltage-gated sodium channel Nav1.7 has gained traction as a pain target with recognition that loss-of-function mutations in SCN9A, the gene encoding Nav1.7, are associated with congenital insensitivity to pain, whereas gain-of-functi...

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Bibliographic Details
Main Author: Dustrude, Erik Thomas
Other Authors: Brustovetsky, Nickolay
Language:en_US
Published: 2015
Subjects:
collapsin response mediator protein
CRMP2
Nav1.7
phosphorylation
SUMOylation
voltage gated sodium channel
Pain perception
Sodium channels
Electrophysiology
Calcium channels > Research
Neurotransmitters
Phosphoproteins
Online Access:http://hdl.handle.net/1805/7348

Internet

http://hdl.handle.net/1805/7348

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