Identification and characterization of small-molecule inhibitors of aldehyde dehydrogenase 1A1

Identification and characterization of small-molecule inhibitors of aldehyde dehydrogenase 1A1

Indiana University-Purdue University Indianapolis (IUPUI) === The human genome encodes 19 members of the aldehyde dehydrogenase (ALDH) superfamily, critical enzymes involved in the metabolism of aldehyde substrates. A major function of the ALDH1A subfamily is the oxidation of retinaldehyde to retino...

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Bibliographic Details
Main Author: Morgan, Cynthia A.
Other Authors: Hurley, Thomas D., 1961-
Language:en_US
Published: 2015
Subjects:
Enzyme kinetics
Small molecule inhibitors
X-ray crystallography
Aldehyde dehydrogenase
Human genome
Oxidation
Molecule-molecule collisions
Enzyme inhibitors
X-ray crystallography - Technique
Online Access:http://hdl.handle.net/1805/6593

Internet

http://hdl.handle.net/1805/6593

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