An IL-4-dependent macrophage-iNKT cell circuit resolves sterile inflammation and is defective in mice with chronic granulomatous disease

An IL-4-dependent macrophage-iNKT cell circuit resolves sterile inflammation and is defective in mice with chronic granulomatous disease

Indiana University-Purdue University Indianapolis (IUPUI) === The immune system initiates tissue repair following injury. In response to sterile tissue injury, neutrophils infiltrate the tissue to remove tissue debris and subsequently undergo apoptosis. Proper clearance of apoptotic neutrophils in t...

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Bibliographic Details
Main Author: Zeng, Melody Yue
Other Authors: Dinauer, Mary D.
Language:en_US
Published: 2014
Subjects:
Immune system > Research > Methodology
Tissues > Research
Chronic granulomatous disease > Research
Guanosine triphosphatase
Killer cells
Neutrophils > Immunology
Inflammation > Research > Evaluation
Apoptosis
Cellular signal transduction > Research
Macrophages > Activation
Phagocytes
Autocrine mechanisms
Paracrine mechanisms
Cytokines
Active oxygen > Physiological effect
Mice as laboratory animals > Research
Online Access:http://hdl.handle.net/1805/3914

Internet

http://hdl.handle.net/1805/3914

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