F-Actin regulation of SNARE-mediated insulin secretion
Indiana University-Purdue University Indianapolis (IUPUI) === In response to glucose, pancreatic islet beta cells secrete insulin in a biphasic manner, and both phases are diminished in type 2 diabetes. In beta cells, cortical F-actin beneath the plasma membrane (PM) prevents insulin granule access...
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| Language: | en_US |
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2013
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| Online Access: | http://hdl.handle.net/1805/3624 |