CaMKII Phosphorylation of the Voltage-Gated Sodium Channel Nav1.6 Regulates Channel Function and Neuronal Excitability

CaMKII Phosphorylation of the Voltage-Gated Sodium Channel Nav1.6 Regulates Channel Function and Neuronal Excitability

Indiana University-Purdue University Indianapolis (IUPUI) === Voltage-gated sodium channels (Navs) undergo remarkably complex modes of modulation to fine tune membrane excitability and neuronal firing properties. In neurons, the isoform Nav1.6 is highly enriched at the axon initial segment and nodes...

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Bibliographic Details
Main Author: Zybura, Agnes Sara
Other Authors: Cummins, Theodore R.
Language:en_US
Published: 2021
Subjects:
CaMKII
Electrophysiology
Nav1.6
Phosphorylation
Post-translational modification
Sodium channel
Online Access:http://hdl.handle.net/1805/25294

Internet

http://hdl.handle.net/1805/25294

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