GATING OF THE SENSORY NEURONAL VOLTAGE-GATED SODIUM CHANNEL NAv1.7: ANALYSIS OF THE ROLE OF D3 AND D4 / S4-S5 LINKERS IN TRANSITION TO AN INACTIVATED STATE

Indiana University-Purdue University Indianapolis (IUPUI) === Voltage-gated sodium channels (VGSCs) are dynamic membrane-spanning proteins crucial for determining the electrical excitability in nerve and muscle. VGSCs transition, or gate, between opened, closed, and inactivated states, in response t...

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Bibliographic Details
Main Author: Jarecki, Brian W.
Other Authors: Cummins, Theodore R.
Language:en_US
Published: 2010
Subjects:
IEM
Online Access:http://hdl.handle.net/1805/2119