Mutant P53 in pre-leukemic hematopoietic stem cells and the pathogenesis of Myelodysplastic Syndrome
Indiana University-Purdue University Indianapolis (IUPUI) === Myelodysplastic syndrome (MDS) is a clonal disease arising from mutated hematopoietic stem cells (HSCs). MDS stem cells originate from pre-leukemic HSCs, which have enhanced competitive advantage over wild-type (WT) HSCs but normal dif...
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Language: | en_US |
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2018
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Online Access: | http://hdl.handle.net/1805/16283 https://doi.org/10.7912/C2MW81 |