Role of ATF4 in directing gene expression in the basal state and during the unfolded protein response in liver

Role of ATF4 in directing gene expression in the basal state and during the unfolded protein response in liver

Indiana University-Purdue University Indianapolis (IUPUI) === Disturbances in membrane composition and protein folding in the endoplasmic reticulum (ER) trigger the unfolded protein response (UPR). Three UPR sensory proteins, PERK (PEK/EIF2AK3), IRE1, and ATF6 are each activated by ER stress. PERK...

Full description

Bibliographic Details
Main Author: Fusakio, Michael Edward
Other Authors: Wek, Ronald C.
Language:en_US
Published: 2016
Subjects:
ATF4
Next generation sequencing
Unfolded protein
Cellular stress
Endoplasmic reticulum
Proteins
Protein folding
Cellular signal transduction
Stress (physiology)
Proteins > Synthesis
Fatty liver
Cholesterol
Gene expression
Online Access:http://hdl.handle.net/1805/11001

Internet

http://hdl.handle.net/1805/11001

Similar Items