Characterization of Host Protein Interactions with HCV RNA : Implications in Viral Translation, Replication and Design of Antivirals
HCV genome is a positive sense single-stranded RNA containing a single open reading frame (ORF) flanked by untranslated regions (UTRs), 5’UTR and 3’UTR.Initiation of HCV RNA translation is mediated by internal ribosome entry site (IRES) present in 5’ UTR and this process is independent of cap-struct...
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Language: | en_US |
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2018
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Online Access: | http://etd.iisc.ernet.in/2005/3496 http://etd.iisc.ernet.in/abstracts/4363/G26604-Abs.pdf |