Unfolding the Mechanism of Notch1 Receptor Activation : Implications in Cancer Stem Cell Targeting
Notch receptors and ligands are single-pass transmembrane proteins which play important roles in cell-cell communication. Notch in ‘harmony’ with other signaling pathways regulate the entire diversity of metazoan life (Artavanis-Tsakonas & Muskavitch, 2010). These signaling pathways also play ke...
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Language: | en_US |
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2018
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Online Access: | http://etd.iisc.ernet.in/2005/3472 http://etd.iisc.ernet.in/abstracts/4339/G25894-Abs.pdf |