Deciphering Structure-Function Relationships in a Two-Subunit-Type GMP Synthetase by Solution NMR Spectroscopy

Deciphering Structure-Function Relationships in a Two-Subunit-Type GMP Synthetase by Solution NMR Spectroscopy

The guanosine monophosphate synthetase (GMPS) is a class I glutamine amidotransferase, involved in the de-novo purine nucleotide biosynthesis. The enzyme catalyzes the biochemical transformation of xantosine (XMP) into guanosine monophosphate (GMP) in presence of ATP, Mg2+ and glutamine. All GMPSs c...

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Bibliographic Details
Main Author: Ali, Rustam
Other Authors: Sarma, Siddhartha P
Language:en_US
Published: 2018
Subjects:
Glutamine Aminotrasferases (GATs)
Guanosine Monophosphate Synthetase
Nuclear Magnetic Resonance (NMR) Spectroscopy
Methanocaldococcus Jannaschii (Mj) GMP Synthetase
GMP Synthetase - Structural Properties
GMP Synthetase - Functional Properties
Methanocaldococcus Jannaschii (Mj) GATase
Protein-Ligand Interactions
Solution NMR Spectroscopy
GMP Synthetase (GMPS)
Mj GATase Subunit
Mj GMP Synthetase
Glutamine Amido Transferase
Methanocaldococcus jannaschii
Biochemistry
Online Access:http://etd.iisc.ernet.in/2005/3454
http://etd.iisc.ernet.in/abstracts/4321/G25980-Abs.pdf

Internet

http://etd.iisc.ernet.in/2005/3454
http://etd.iisc.ernet.in/abstracts/4321/G25980-Abs.pdf

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