Determination of absorption curves, dissolution profiles and establishment of in vitro-in vivo correlation by in silico methods using GastroPlusTM and DDDPlusTM

The use of computer programs to predict drug absorption in humans and to simulate dissolution profiles has become a valuable tool in the pharmaceutical area. The objective of this study was to use in silico methods through software GastroPlusTM and DDDPlusTM to simulate drug absorption curves an...

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Bibliographic Details
Main Author: Marcelo Dutra Duque
Other Authors: Humberto Gomes Ferraz
Language:English
Published: Universidade de São Paulo 2016
Subjects:
Online Access:http://www.teses.usp.br/teses/disponiveis/9/9139/tde-13042016-150335/