Efeito neuroprotetor dos moduladores alostéricos positivos do receptor metabotrópico de glutamato 5 na doença de Huntington
=== Huntington's disease (HD) is a neurodegenerative disorder, progressive and hereditary, that evolves inevitably to death. Stimulation of metabotropic glutamate receptor 5 (mGluR5), which is coupled to Gq, promotes increased levels of IP3 and intracellular Ca2+, which can cause excitotoxicit...
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Format: | Others |
Language: | Portuguese |
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Universidade Federal de Minas Gerais
2013
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Online Access: | http://hdl.handle.net/1843/BUOS-9PFJ6L |