Efeito neuroprotetor dos moduladores alostéricos positivos do receptor metabotrópico de glutamato 5 na doença de Huntington

=== Huntington's disease (HD) is a neurodegenerative disorder, progressive and hereditary, that evolves inevitably to death. Stimulation of metabotropic glutamate receptor 5 (mGluR5), which is coupled to Gq, promotes increased levels of IP3 and intracellular Ca2+, which can cause excitotoxicit...

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Bibliographic Details
Main Author: Juliana Guimaraes Doria
Other Authors: Fabiola Mara Ribeiro
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2013
Online Access:http://hdl.handle.net/1843/BUOS-9PFJ6L