DNA polimerase beta: uma proteína envolvida na replicação e reparo do DNA mitocondrial em Trypanosoma cruzi

=== During its life cycle, the causative agent of Chagas Disease Trypanosoma cruzi must deal with the deleterious action of reactive oxygen species (ROS) on DNA, mainly 7,8-dihydro-8-oxoguanine (8oxoG). If unrepaired, 8oxoG can lead to transversions during cell division. In mammals, DNA polymerase...

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Bibliographic Details
Main Author: Bruno Luiz Fonseca Schamber Reis
Other Authors: Carlos Renato Machado
Format: Others
Language:Portuguese
Published: Universidade Federal de Minas Gerais 2010
Online Access:http://hdl.handle.net/1843/BUOS-9ADHF3