Mechanistic study on the inhibition of the late stage of basal autophagy progression by a natural compound (NAADP) and a synthetic small chemical (vacuolin-1)
Autophagy is a catabolic lysosomal degradation process essential for cellular homeostasis and cell survival. Dysfunctional autophagy has been associated with wide ranges of human diseases, e.g. cancer and neurodegenerative diseases. Although enormous progress has been made on the core molecular mach...
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Language: | English |
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The University of Hong Kong (Pokfulam, Hong Kong)
2014
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Online Access: | http://hdl.handle.net/10722/207179 |