Effect of flavonols on the activity of arginase and the action of nitroglycerin in endothelial cells with and without previous exposure to nitroglycerin

Organic nitrates have been effective treatment for ischemic heart disease for over 100 years. However, there is limitation in their clinical utility since prolonged use of these drugs results in rapid development of nitrate tolerance, which is associated with increased arginase activity and producti...

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Bibliographic Details
Main Authors: Jen, Che-lung, 任志龍
Language:English
Published: The University of Hong Kong (Pokfulam, Hong Kong) 2014
Subjects:
Online Access:http://hdl.handle.net/10722/206500