Interrelationship between SIRT1 function and biotin homeostasis : implications in metabolic ageing
SIRT1 (sirtuin 1) is a mammalian homolog of the longevity regulator Sir2p in yeast which catalyzes the removal of acetyl groups from protein substrates. Mammalian SIRT1 acts as an energy and stress sensor contributing to the beneficial effects of calorie restriction by regulating the acetylation sta...
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| Language: | English |
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The University of Hong Kong (Pokfulam, Hong Kong)
2014
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| Online Access: | http://hdl.handle.net/10722/196431 |