Spectroscopic Investigation into Minor Groove Binders Designed to Selectively Target DNA Sequences

Recently, there has been increasing focus toward the development of small molecules designed to target a specific sequences of double stranded DNA for therapeutic purposes1. Minor groove binding compounds have been shown to be capable of selectivity target GC sites in AT tract DNA2. In this research...

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Bibliographic Details
Main Author: Walton, Joseph
Format: Others
Published: ScholarWorks @ Georgia State University 2015
Subjects:
DNA
Online Access:http://scholarworks.gsu.edu/chemistry_theses/82
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1082&context=chemistry_theses