One DNA minor groove, many possibilities: from sequence recognition to transcription factor inhibition
Natural and synthetic heterocyclic cations that bind to the DNA minor groove have demonstrated effectiveness as therapeutic agents for cancer, parasitic and viral diseases, as well as powerful probes for use to extend our fundamental understanding of DNA molecular recognition. Crystal and NMR struct...
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ScholarWorks @ Georgia State University
2014
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| Online Access: | http://scholarworks.gsu.edu/chemistry_diss/95 http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1100&context=chemistry_diss |