Dynamic Regulation of the Class II Transactivator by Posttranslational Modifications

The class II Transactivator (CIITA) is the master regulator for Major Histocompatibility Class II (MHC II) molecules. CIITA is dynamically regulated by a series of Posttranslational Modifications (PTMs). CIITA is responsible for initiating transcription of MHC II genes, thus allowing peptides derive...

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Bibliographic Details
Main Author: Morgan, Julie E
Format: Others
Published: ScholarWorks @ Georgia State University 2015
Subjects:
Online Access:http://scholarworks.gsu.edu/biology_diss/157
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1162&context=biology_diss