Extracellular Pyruvate Kinase M2 regulates tumor angiogenesis

Pyruvate kinase M2 (PKM2) has been studied for decades on its role in cancer metabolism. Recently, PKM2 is highlighted again for its new function: promoting gene transcription by acting as a protein kinase. Moreover, the PKM2 levels in patient circulation have been used as a diagnostic marker for ma...

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Bibliographic Details
Main Author: Li, Liangwei
Format: Others
Published: ScholarWorks @ Georgia State University 2014
Subjects:
Online Access:http://scholarworks.gsu.edu/biology_diss/141
http://scholarworks.gsu.edu/cgi/viewcontent.cgi?article=1146&context=biology_diss