Advanced Designs of Cancer Phase I and Phase II Clinical Trials
The clinical trial is the most import study for the development of successful novel drugs. The aim of this dissertation is to develop innovative statistical methods to overcome the three main obstacles in clinical trials: (1) lengthy trial duration and inaccurate maximum tolerated dose (MTD) in phas...
| Main Author: | |
|---|---|
| Format: | Others |
| Published: |
Digital Archive @ GSU
2013
|
| Subjects: | |
| Online Access: | http://digitalarchive.gsu.edu/math_diss/15 http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1013&context=math_diss |