Effects of Temperature on the Kinetic Isotope Effects for Proton and Hydride Transfers in the Active Site Variant of Choline Oxidase Ser101Ala

Choline oxidase catalyzes the oxidation of choline to glycine betaine. The reaction includes betaine aldehyde as an intermediate. FAD is reduced by the alcohol substrate, betaine aldehyde intermediate and oxidized by molecular oxygen to give hydrogen peroxide. In this study, the Ser101Ala variant of...

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Bibliographic Details
Main Author: Uluisik, Rizvan C
Format: Others
Published: Digital Archive @ GSU 2013
Subjects:
Online Access:http://digitalarchive.gsu.edu/chemistry_theses/56
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1055&context=chemistry_theses