Synthesis of 2,4-Disubstituted Pyrimidine Derivatives as Potential 5-HT7 Receptor Antagonist.
The synthesis of a series of 2-chloropyrimidine derivatives is described. The synthesis began with a nucleophilic addition of lithiated heterocyclic molecules to the 4 position of 2-chloropyrimidine to give dihydropyrimidine intermediates. The intermediates were oxidized to the pyrimidine ring usin...
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| Format: | Others |
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Digital Archive @ GSU
2008
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| Online Access: | http://digitalarchive.gsu.edu/chemistry_theses/11 http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1010&context=chemistry_theses |