Kinetic Mechanism and Inhibitory Study of Protein Arginine Methyltransferase 1

Protein arginine methyltransferase 1 (PRMT1) is a key posttranslational modification enzyme that catalyzes the methylation of specific arginine residues in histone and nonhistone protein substrates, regulating diverse cellular processes such as transcriptional initiation, RNA splicing, DNA repair, a...

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Bibliographic Details
Main Author: Feng, You
Format: Others
Published: Digital Archive @ GSU 2012
Subjects:
Online Access:http://digitalarchive.gsu.edu/chemistry_diss/68
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1065&context=chemistry_diss