Sequence-Specific and Conformation-Specific Targeting of Duplex and Quadruplex DNA Grooves with Small Molecules

Small molecule mediated chemical intervention of biological processes using nucleic acid targets has proven extremely successful and is continually providing exciting new avenues for the development of anti-cancer agents and molecular probes. Among the alternative DNA confrormations, G-quadruplexes...

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Bibliographic Details
Main Author: Nanjunda, Rupesh K
Format: Others
Published: Digital Archive @ GSU 2010
Subjects:
Online Access:http://digitalarchive.gsu.edu/chemistry_diss/47
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1049&context=chemistry_diss