Sequence-Specific and Conformation-Specific Targeting of Duplex and Quadruplex DNA Grooves with Small Molecules
Small molecule mediated chemical intervention of biological processes using nucleic acid targets has proven extremely successful and is continually providing exciting new avenues for the development of anti-cancer agents and molecular probes. Among the alternative DNA confrormations, G-quadruplexes...
Main Author: | |
---|---|
Format: | Others |
Published: |
Digital Archive @ GSU
2010
|
Subjects: | |
Online Access: | http://digitalarchive.gsu.edu/chemistry_diss/47 http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1049&context=chemistry_diss |