Determining The Site Specific Metal Binding and Structural Properties of EF-Hand Protein Using Grafting Approach
Calmodulin is an essential EF-hand protein with a helix-loop-helix calcium binding motif. Understanding Ca(II) dependent activation of calmodulin and other EF-hand proteins is limited by Ca(II)-induced conformational change, multiple and cooperative binding of Ca(II) ions, and interactions between...
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Digital Archive @ GSU
2008
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Online Access: | http://digitalarchive.gsu.edu/chemistry_diss/26 http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1025&context=chemistry_diss |