The Role of Rankl in Prostate Cancer Progression and Bone Metastasis

This study focused on the role of RANKL in prostate cancer EMT progression and metastasis. Activation of RANK, a receptor activator of NF-kB, by its ligand RANKL, in a paracrine manner is responsible for osteoclast differentiation and bone remodeling. RANK activation in cancer cells, however, is tho...

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Bibliographic Details
Main Author: Chu, Chia-Yi
Format: Others
Published: Digital Archive @ GSU 2011
Subjects:
Online Access:http://digitalarchive.gsu.edu/biology_diss/118
http://digitalarchive.gsu.edu/cgi/viewcontent.cgi?article=1121&context=biology_diss