Shear stress, hemodynamics, and proteolytic mechanisms underlying large artery remodeling in sickle cell disease
Sickle cell disease is a genetic disorder that affects 100,000 Americans and millions more worldwide. Although the sickle mutation affects one protein, which is only expressed in a single cell type, it has profound detrimental effects on nearly every organ system in the body. Young children with s...
Main Author: | |
---|---|
Other Authors: | |
Format: | Others |
Language: | en_US |
Published: |
Georgia Institute of Technology
2016
|
Subjects: | |
Online Access: | http://hdl.handle.net/1853/54289 |