Detection and characterization of gene-fusions in breast and ovarian cancer using high-throughput sequencing

Detection and characterization of gene-fusions in breast and ovarian cancer using high-throughput sequencing

Gene-fusions are a prevalent class of genetic variants that are often employed as cancer biomarkers and therapeutic targets. In recent years, high-throughput sequencing of the cellular genome and transcriptome have emerged as a promising approach for the investigation of gene-fusions at the DNA and...

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Bibliographic Details
Main Author: Mittal, Vinay K.
Other Authors: McDonald, John F.
Format: Others
Language:en_US
Published: Georgia Institute of Technology 2015
Subjects:
Cancer
RNA-Seq
Whole-genome sequencing
Gene-fusion
Bioinformatics
Chimeric transcript
Pipeline
Transcriptomics
Genomics
Next-generation sequencing
High-throughput sequencing
Online Access:http://hdl.handle.net/1853/54014

Internet

http://hdl.handle.net/1853/54014

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