Copper(I)-catalyzed azide-alkyne cycloaddition with membrane bound lipid substrates

The bioorthogonal copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction exhibits complex but well-defined kinetics in aqueous and organic solution for soluble azides, alkynes, and ligand-bound copper(I). The kinetic profile in two dimensions, however, for CuAAC systems within a lipid bilay...

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Bibliographic Details
Main Author: Beveridge, Jennifer Marie
Other Authors: Finn, M. G.
Format: Others
Language:en_US
Published: Georgia Institute of Technology 2015
Subjects:
Online Access:http://hdl.handle.net/1853/53594