Copper(I)-catalyzed azide-alkyne cycloaddition with membrane bound lipid substrates
The bioorthogonal copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction exhibits complex but well-defined kinetics in aqueous and organic solution for soluble azides, alkynes, and ligand-bound copper(I). The kinetic profile in two dimensions, however, for CuAAC systems within a lipid bilay...
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Format: | Others |
Language: | en_US |
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Georgia Institute of Technology
2015
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Online Access: | http://hdl.handle.net/1853/53594 |