Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease
The inherited form of primary open angle glaucoma, a disorder characterized by increased intraocular pressure and retina degeneration, is linked to mutations in the olfactomedin (OLF) domain of the myocilin gene. Disease-causing myocilin variants accumulate within trabecular meshwork cells instead o...
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Georgia Institute of Technology
2013
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| Online Access: | http://hdl.handle.net/1853/45816 |