Broadening the enyzme-catalyzed synthesis of semi-synthetic antibiotics
An alpha-amino ester hydrolase (AEH) applicable to synthesis of semi-synthetic antibiotics was cloned from the genomic DNA of Xanthomonas campestris pv. campestris sp. strain ATCC 33913. AEHs catalyze the synthesis and hydrolysis of alpha-amino beta-lactam antibiotics. The enzyme was characterized f...
Main Author: | |
---|---|
Published: |
Georgia Institute of Technology
2011
|
Subjects: | |
Online Access: | http://hdl.handle.net/1853/39528 |