Conservation of mechanosignaling: responses of human adult mesenchymal stem cells and differentiated vascular cells to applied physical forces

Conservation of mechanosignaling: responses of human adult mesenchymal stem cells and differentiated vascular cells to applied physical forces

Mesenchymal stem cells (MSCs) may benefit vascular cell-based therapies as smooth muscle or endothelial cell substitutes or through paracrine actions to repair, replace, or regenerate vascular tissue. Previous studies have demonstrated that MSCs can adopt traits of smooth muscle cells (SMCs) or endo...

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Bibliographic Details
Main Author: Doyle, Adele Marion
Published: Georgia Institute of Technology 2011
Subjects:
Tissue engineering
Extracellular matrix protein
Cardiovascular
MSC
Highthroughput
Vascular graft
Substrate
Mechanobiology
Regenerative medicine
Mesenchymal stem cells
Blood-vessels
Cellular signal transduction
Biomechanics
Shear flow
Endothelium Mechanical properties
Strains and stresses
Online Access:http://hdl.handle.net/1853/39526

Internet

http://hdl.handle.net/1853/39526

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