Engineering and improving a molecular switch system for gene therapy applications

Molecular switch systems that activate gene expression by a small molecule are effective technologies that are widely used in applied biological research. Previously, two orthogonal ligand receptor pairs (OLRP) were developed as potential molecular switch systems by modifying nuclear receptors, liga...

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Bibliographic Details
Main Author: Taylor, Jennifer
Published: Georgia Institute of Technology 2011
Subjects:
RXR
Online Access:http://hdl.handle.net/1853/39501