Monitoring dynamic calcium homeostasis alterations by T₁-weighted and T₁-mapping cardiac manganese enhanced MRI (MEMRI) in a murine myocardial infarction model

Manganese has been used as a T₁-weighted MRI contrast agent in a variety of applications. Because manganese ions (Mn²) enter viable myocardial cells via voltage gated calcium channels, manganese-enhanced MRI (MEMRI) is sensitive to the viability and the inotropic state of the heart. In spite of the...

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Bibliographic Details
Main Author: Waghorn, Benjamin J.
Published: Georgia Institute of Technology 2009
Subjects:
Online Access:http://hdl.handle.net/1853/28237