Regulation of endothelial gene transcription by shear stress in a manner dependent on p47phox-based NADPH oxidases
Atherosclerosis occurs preferentially at branches and curves in arteries exposed to disturbed flow while sparing straight portions of arteries exposed to undisturbed flow. In vivo and in vitro studies have implicated NADPH oxidases in atherosclerosis and hypertension. Shear stress can induce react...
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Georgia Institute of Technology
2008
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| Online Access: | http://hdl.handle.net/1853/24824 |