Dual Osteogenic and Angiogenic Growth Factor Delivery as a Treatment for Segmental Bone Defects

A new model of a critically-sized segmental femoral bone defect in rats was developed to enable in vivo imaging and facilitate post-mortem mechanical testing of samples. The critically-sized nature of the model was assessed and confirmed. The efficacy of sustained co-delivery of osteogenic (BMP-2 an...

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Bibliographic Details
Main Author: Oest, Megan Elizabeth
Published: Georgia Institute of Technology 2007
Subjects:
Online Access:http://hdl.handle.net/1853/16264