Design, synthesis, and evaluation of fluorescent sensors for intracellular imaging of monovalent copper
The main theme of this thesis is to develop a fluorescent probe for imaging the subcellular distribution of kinetically labile copper pools that might play a critical role in copper homeostasis. Various copper-selective sensors were designed by combining 1,3,5-triaryl-2-pyrazoline fluorophores with...
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Format: | Others |
Language: | en_US |
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Georgia Institute of Technology
2006
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Online Access: | http://hdl.handle.net/1853/11655 |