Improving Relative Bioavailability of Orally Dosed Aliskiren through Poly(lactic-co-glycolic) Acid Nanoformulation in Rats

Improving Relative Bioavailability of Orally Dosed Aliskiren through Poly(lactic-co-glycolic) Acid Nanoformulation in Rats

Purpose: Athough an effective direct renin inhibitor, aliskiren (ALS) presents with a low bioavailability coupled with high drug cost. As nanoformulation may increase drug bioavailability, our laboratory developed an ALS-loaded poly(lactic-co-glycolic) acid nanoparticle (ALS-NP) formulation. As suc...

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Bibliographic Details
Main Authors: Murrell, Derek, Brown, Stacy D., Lawson-Hellu, Fessou Eke, Harirforoosh, Sam
Published: Digital Commons @ East Tennessee State University 2017
Subjects:
orally dosed aliskiren
poly acid
bioavailability
Pharmaceutical Sciences
Chemicals and Drugs
Pharmacy and Pharmaceutical Sciences
Online Access:https://dc.etsu.edu/etsu-works/5269

Internet

https://dc.etsu.edu/etsu-works/5269

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