Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia

Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia

The current study analyzed the effects of environmental enrichment versus isolation housing on the behavioral sensitization to nicotine in the neonatal quinpirole (NQ; dopamine D2-like agonist) model of dopamine D2 receptor supersensitivity, a rodent model of schizophrenia. NQ treatment in rats incr...

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Bibliographic Details
Main Authors: Brown, Russell W., Schlitt, Marjorie A., Owens, Alex S., DePreter, Caitlynn C., Cummins, Elizabeth D., Kirby, Seth L., Gill, W. Drew, Burgess, Katherine C.
Published: Digital Commons @ East Tennessee State University 2018
Subjects:
dopamine
dopamine receptor
developing brain
animal model
neurotrophic factor
nucleus accumbens
schizophrenia
Biomedical Sciences
Substance Abuse and Addiction
Online Access:https://dc.etsu.edu/etsu-works/2767
https://doi.org/10.1159/000486391

Internet

https://dc.etsu.edu/etsu-works/2767
https://doi.org/10.1159/000486391

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