Sex and Dose-Related Differences in Methylphenidate Adolescent Locomotor Sensitization and Effects on Brain-Derived Neurotrophic Factor

Sex and Dose-Related Differences in Methylphenidate Adolescent Locomotor Sensitization and Effects on Brain-Derived Neurotrophic Factor

This study analyzed repeated methylphenidate (MPH) administration and its effects on brain-derived neurotrophic factor (BDNF) in the dorsal striatum and nucleus accumbens of male and female adolescent rats. In Experiment 1, rats were administered intraperitoneal (ip) saline, 1, 3, or 5 mg/kg dose of...

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Bibliographic Details
Main Authors: Brown, Russell W., Hughes, Benjamin A, Hughes, Andrew B., Sheppard, A. Brianna, Perna, Marla K., Ragsdale, W Lee, Roeding, Ross L., Pond, Brooks B., Pharmaceutical Sciences
Published: Digital Commons @ East Tennessee State University 2012
Subjects:
adolescent
behavioral sensitization
brain-derived neutrophic factor
methylphenidate
rats
ritalin
sex differences
striatum
Biomedical Sciences
Neurosciences
Pharmacy and Pharmaceutical Sciences
Online Access:https://dc.etsu.edu/etsu-works/958
https://doi.org/10.1177/0269881112454227

Internet

https://dc.etsu.edu/etsu-works/958
https://doi.org/10.1177/0269881112454227

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