Concomitant Gene Mutations of MBL and CYBB In Chronic Granulomatous Disease: Implications For Host Defense

Concomitant Gene Mutations of MBL and CYBB In Chronic Granulomatous Disease: Implications For Host Defense

Chronic granulomatous disease (CGD) is associated with defective function of the NADPH-oxidase system in conjunction with phagocytic defects which leads to granuloma formation and serious infectious complications. This is often associated with significant morbidity and mortality. The association of...

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Bibliographic Details
Main Authors: Watkins, Casey E., Saleh, Hana, Song, Eunkyung, Jaishankar, Gayatri B., Chi, David S., Misran, Niva, Peiris, Emma, Altrich, Michelle L., Barklow, Thomas, Krishnaswamy, Guha
Published: Digital Commons @ East Tennessee State University 2012
Subjects:
chronic granulomatous disease
complement
immune deficiency
innate immunity
mannose binding protein deficiency
nadph oxidase
opportunistic infections
phagocyte
Pediatrics
Online Access:https://dc.etsu.edu/etsu-works/8956
https://doi.org/10.2174/187152812800392724

Internet

https://dc.etsu.edu/etsu-works/8956
https://doi.org/10.2174/187152812800392724

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