Behavioral and Neurobiological Evidence of Epigenetic Transmission in the Neonatal Quinpirole Rodent Model of Schizophrenia
Quinpirole is a dopamine D2 receptor agonist that if administered to rats from postnatal day (P)1-21 results in increased dopamine D2 receptor sensitivity throughout the animal’s lifetime. This increase in receptor sensitivity is consistent with schizophrenia. This model has additional consistencies...
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Format: | Others |
Language: | English |
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Digital Commons @ East Tennessee State University
2020
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Online Access: | https://dc.etsu.edu/etd/3719 https://dc.etsu.edu/cgi/viewcontent.cgi?article=5197&context=etd |