HIF-1α in the Heart: Provision of Ischemic Cardioprotection and Remodeling of Nucleotide Metabolism
In our studies we found that stabilized expression of HIF-1α in heart led to better recovery of function and less tissue death after 30 minutes of global ischemia, via mechanisms that preserve the mitochondrial polarization. Our group previously showed that HIF-1α conferred ischemic tolerance by all...
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| Format: | Others |
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Digital Commons @ East Tennessee State University
2014
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| Online Access: | https://dc.etsu.edu/etd/2450 https://dc.etsu.edu/cgi/viewcontent.cgi?article=3824&context=etd |