Novel Therapeutic Approaches for Ischemic Heart and Brain Injury: Modulation of Toll-Like Receptor-Mediated Signaling Pathways and PI3K/Akt Signaling
Innate immune and inflammatory responses contribute to myocardial and cerebral ischemia/reperfusion (I/R) injury. Toll-like receptors (TLRs) play a critical role in the induction of innate immune and inflammatory responses via activation of nuclear factor kappa B (NF-κB). We have shown that activati...
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| Format: | Others |
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Digital Commons @ East Tennessee State University
2014
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| Online Access: | https://dc.etsu.edu/etd/2343 https://dc.etsu.edu/cgi/viewcontent.cgi?article=3709&context=etd |