The Signaling Pathway of Oxysterol-Induced Apoptosis in Macrophages.

The Signaling Pathway of Oxysterol-Induced Apoptosis in Macrophages.

Oxidized low-density lipoproteins (OxLDL) mediate many of the pathological events associated with atherosclerosis. Oxysterols, the major cytotoxic component of OxLDL, induce apoptosis in macrophages by a calcium flux mediated activation of cytosolic phospholipase A2 resulting in the release of arach...

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Bibliographic Details
Main Author: Freeman, Natalie Elaine
Format: Others
Published: Digital Commons @ East Tennessee State University 2005
Subjects:
Cannabinoid Receptors
ACAT
Eicosanoids
Oxysterols
Oxidized low density lipoproteins
Macrophages
Apoptosis
Oxysteryl Ester
Medical Sciences
Medicine and Health Sciences
Online Access:https://dc.etsu.edu/etd/1063
https://dc.etsu.edu/cgi/viewcontent.cgi?article=2220&context=etd

Internet

https://dc.etsu.edu/etd/1063
https://dc.etsu.edu/cgi/viewcontent.cgi?article=2220&context=etd

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