Role of Zmpste24 in Prelamin A Maturation.

The nuclear lamins form a karyoskeleton providing structural rigidity to the nucleus. One member of the lamin family, lamin A, is first synthesized as a 74 kDa precursor, prelamin A. Following the endopeptidase and methylation reactions which occur after farnesylation of the CAAX-box cysteine, there...

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Bibliographic Details
Main Author: Corrigan, Douglas Paul
Format: Others
Published: Digital Commons @ East Tennessee State University 2005
Subjects:
Online Access:https://dc.etsu.edu/etd/1046
https://dc.etsu.edu/cgi/viewcontent.cgi?article=2203&context=etd