Role of Zmpste24 in Prelamin A Maturation.
The nuclear lamins form a karyoskeleton providing structural rigidity to the nucleus. One member of the lamin family, lamin A, is first synthesized as a 74 kDa precursor, prelamin A. Following the endopeptidase and methylation reactions which occur after farnesylation of the CAAX-box cysteine, there...
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Digital Commons @ East Tennessee State University
2005
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Online Access: | https://dc.etsu.edu/etd/1046 https://dc.etsu.edu/cgi/viewcontent.cgi?article=2203&context=etd |